Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice
نویسندگان
چکیده
منابع مشابه
Therapeutic Effect of Astragalus Polysaccharides on Hepatocellular Carcinoma H22-Bearing Mice
The purpose of this study was to investigate the effect of astragalus polysaccharides (APSs), active constituents of astragalus, in the treatment of hepatocellular carcinoma (HCC) and their potential as a promising candidate for future anticancer drug development. Astragalus polysaccharide was administered at different doses to HCC H22-bearing mice to investigate their antitumor effects. Result...
متن کاملEffects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro
BACKGROUND Astragalus polysaccharides (APS) are active constituents of Astragalus membranaceus. They have been widely studied, especially with respect to their immunopotentiating properties, their ability to counteract the side effects of chemotherapeutic drugs, and their anticancer properties. However, the mechanism by which APS inhibit cancer and the issue of whether that mechanism involves t...
متن کاملRegulatory effect of astragalus polysaccharides on intestinal intraepithelial γδT cells of tumor bearing mice.
Astragalus polysaccharides (APS) possess multiple immunomodulatory activities. Due to its high molecular weight, orally administration of APS is not easily absorbed into the blood stream, and how APS exerts its capacity in vivo is still not well elucidated. We assume that enteric mucosal immune response might trigger the immune regulation of APS, and our previous studies demonstrated that APS h...
متن کاملEvaluation of Th1 and TH2 Cytokine Network in Aspergilus Infected Tumor Bearing Mice
Background & Objective: Invasive Aspergillosis is a fatal infection in immunocompromised patients. The aim of this study was to evaluate the interaction of infectious with Aspergillus and tumor on immune response and cytokine network in Aspergillus infected tumor-bearing mice. Materials and Methods: Mice were implanted by sterile pieces of mouse mammary tumor and then infected by Aspergillus co...
متن کاملAnti-Tumor Effect of Steamed Codonopsis lanceolata in H22 Tumor-Bearing Mice and Its Possible Mechanism.
Although previous studies confirmed that steaming and the fermentation process could significantly improve the cognitive-enhancement and neuroprotective effects of Codonopsis lanceolata, the anti-tumor efficacy of steamed C. lanceolata (SCL) and what mechanisms are involved remain largely unknown. The present study was designed to evaluate the anti-tumor effect in vivo of SCL in H22 tumor-beari...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2012
ISSN: 1007-9327
DOI: 10.3748/wjg.v18.i47.7079